Detalhe da pesquisa
1.
Neuronal DNA double-strand breaks lead to genome structural variations and 3D genome disruption in neurodegeneration.
Cell
; 186(20): 4404-4421.e20, 2023 09 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37774679
2.
A Cdk5-derived peptide inhibits Cdk5/p25 activity and improves neurodegenerative phenotypes.
Proc Natl Acad Sci U S A
; 120(16): e2217864120, 2023 04 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37043533
3.
iPSC-derived microglia carrying the TREM2 R47H/+ mutation are proinflammatory and promote synapse loss.
Glia
; 72(2): 452-469, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-37969043
4.
TDP-43 mediated blood-brain barrier permeability and leukocyte infiltration promote neurodegeneration in a low-grade systemic inflammation mouse model.
J Neuroinflammation
; 17(1): 283, 2020 Sep 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-32979923
5.
Engineered 3D Immuno-Glial-Neurovascular Human Brain Model.
bioRxiv
; 2023 Aug 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37645757
6.
Accumulation of C-terminal cleaved tau is distinctly associated with cognitive deficits, synaptic plasticity impairment, and neurodegeneration in aged mice.
Geroscience
; 44(1): 173-194, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34410588